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Table 1 Causal associations between methylation and expression of PANoptosis-related genes

From: Targeted multi-layer analysis of PANoptosis-associated genes in the etiology of chronic kidney disease

Expo_ID

Outco_Gene

SYMBOL

p_SMR

p_SMR_multi

fdr_SMR

OR_SMR

95% CI_SMR

cg04033857

ENSG00000110092

CCND1

6.85E-12

6.85E-12

2.28E-11

1.834

1.542–2.181

cg27380288

ENSG00000132518

GUCY2D

0.005426

0.005426

0.006383

0.892

0.823–0.967

cg18944653

ENSG00000019991

HGF

1.67E-06

1.67E-06

2.38E-06

0.841

0.783–0.903

cg23844623

ENSG00000110514

MADD

1.20E-08

1.20E-08

2.40E-08

0.787

0.725–0.855

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Human Genomics

ISSN: 1479-7364