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Fig. 1 | Human Genomics

Fig. 1

From: BAX-mediated ammonia-driven cell death: a novel prognostic and therapeutic target in clear cell renal cell carcinoma

Fig. 1

Construction, validation, and performance assessment of the ammonia death-related prognostic model. (A) Bar chart compares the C-index of different combinations of Cox regression machine learning algorithms across multiple validation queues. (B) The error rate curve shows the convergence of the random survival forest model as the decision tree increases. (C) Bar chart showing the relative importance of ammonia metabolism-related genes in the prognostic model. (D-G) KM (Kaplan-Meier) survival curve and time-dependent ROC (Receiver Operating Characteristic) curve to assess the effectiveness of risk stratification in independent cohorts

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Human Genomics

ISSN: 1479-7364