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Fig. 6 | Human Genomics

Fig. 6

From: Exploring the hepatic-ophthalmic axis through immune modulation and cellular dynamics in diabetic retinopathy and non-alcoholic fatty liver disease

Fig. 6

Convergent Patterns and Robustness of Pseudo-time Analysis in PDR and NAFLD. (A) Trajectory state plots show common seven states in cell clusters between GSE165784 and GSE189175. (B) Trajectory separated cell types in T cells and endothelial cells in both datasets. (C) Pseudo-time kinetics of the top 50 common DEGs in T cells (EST1, PYHIN1, SLC38A1, SYNE2). The dynamic changes of macrophages (MSR1) and endothelial cells (PPFIBP1, LIFR, HSPG2) are shown in Supplementary Figure S1

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