Fig. 1

Flow chart of the study. ScRNA-seq data for PDR and NAFLD were retrieved from the Gene Expression Omnibus (GEO) database. The key cell types were calculated by differential gene expression analysis, following with pseudo-time analysis to delineate dynamic changes in core cells. CellChat was employed to predict intercellular communication and signaling pathways. Additionally, gene set enrichment and variation analyses were performed to uncover key functional enrichments