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Fig. 7 | Human Genomics

Fig. 7

From: The comprehensive potential of AQP1 as a tumor biomarker: evidence from kidney neoplasm cohorts, cell experiments and pan-cancer analysis

Fig. 7

Knockdown of AQP1 in 786-O cells suppressed cell proliferation, migration and invasion. (A) WB validated the stable knockdown of AQP1 in 786-O cells. (B) The CCK-8 assay demonstrated reduced cell proliferation in AQP1 knockdown cells. (C) The colony formation assay revealed that AQP1 knockdown cells formed less colonies than normal controls. (D) The transwell migration assay showed that knockdown of AQP1 suppressed cell migration. (E) The transwell invasion assay showed that AQP1 knockdown cells inhibited cell invasion. (F) The cell scratch assay revealed that knockdown of AQP1 suppressed wound healing. WB, western blot; CCK-8, Cell counting kit-8

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Human Genomics

ISSN: 1479-7364