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Fig. 6 | Human Genomics

Fig. 6

From: The comprehensive potential of AQP1 as a tumor biomarker: evidence from kidney neoplasm cohorts, cell experiments and pan-cancer analysis

Fig. 6

AQP1 expression correlated with tumor immunity and enrichment pathways. (A) The correlation between AQP1 expression and different types of immune cell infiltration of KIRC and KIRP. (B) The heatmap of AQP1 expression and IRGs correlation. The Y-axis displayed the analyzed immune genes, with blue indicating inhibitory genes and red indicating promotive genes. The X-axis represented the cancer type. Asterisks denoted statistical significance. The detailed correlation values were shown in triangles, with blue indicating negative values and red indicating positive values. (C) The plots showed the enrichment score in the top 5 ranked list of pathways influenced by AQP1 expression. The top portion of the plot displayed the name of pathways. The middle portion marked the position of genes within each set across the ranked list, while the bottom plot provides the ranked list metric, illustrating the distribution of the metric scores across all ranked genes. IRGs, immune related genes

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Human Genomics

ISSN: 1479-7364