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Fig. 2 | Human Genomics

Fig. 2

From: The comprehensive potential of AQP1 as a tumor biomarker: evidence from kidney neoplasm cohorts, cell experiments and pan-cancer analysis

Fig. 2

Significant association between AQP1 expression and clinical variables. (A) The violin plot revealed the variances in AQP1 expression between neoplastic and normal tissues (p < 0.001). (B) Survival analysis using the K-M curve showed that individuals with elevated AQP1 expression in their tumor tissues had prolonged OS (p < 0.001). (C) Survival analysis using the K-M curve showed that individuals with elevated AQP1 expression in their tumor tissues had prolonged PFS (p < 0.001). (D) The analysis using Pearson’s Chi-square test revealed that the presence of AQP1 in tumors was significantly linked with the classification of histopathology, T stage, stage, progression after treatment, OS censor, and PFS classification. (E) The forest plot showed the factors that influenced the OS and PFS of renal cancer patients. Elevated AQP1 expression in renal cancer was identified as a protective factor. K-M, Kaplan-Meier; OS, overall survival; PFS, progression-free survival. (F-I) The model diagnosis revealed excellent accuracy and validity

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Human Genomics

ISSN: 1479-7364