Table 1 Demographic and treatment characteristics of the study population
Variables | TRS | non-TRS | p |
|---|---|---|---|
Number of patients, n | 478 | 808 | – |
Male, n (%) | 284 (59) | 430 (53) | 0.031 |
Age, years; mean (SD) | 48.7 (15.0) | 48.7 (16.9) | 0.99 |
Serum concentration, nmol/L; mean (95%CI) | 1201 (1162,1240) | 64 (30, 98) | – |
Dose, mg/day; mean (95%CI) | 335 (320, 350) | 3.3 (3.2, 3.4) | – |
History of TDM measurements, n; median (IQR) | 14 (5, 36) | 3 (1.8, 7) | – |
TDM duration, years; median (IQR) | 4.3 (0.7, 11.8) | 0.8 (0.04, 4.8) | – |