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Fig. 3 | Human Genomics

Fig. 3

From: The T-cell repertoire of Spanish patients with COVID-19 as a strategy to link T-cell characteristics to the severity of the disease

Fig. 3

Main results of the GLIPH2 analysis. (A) Network with the 36 global and local clusters initially identified after selection of the 100 most expanded clonotypes of each repertoire. (B) Box-violin plot of the 4 clusters identified by GLIPH2 after selection and filtering of CDR3b COVID + sequences and with significant changes between age and sex groups. (C) Sequence logos of the CDR3b COVID + sequences of each GLIPH2 cluster shown in (B). Mann-Whitney U test test was performed for two-group comparisons and one-way Kruskal-Wallis test for 4-group comparisons plus Dunn’s test and corrected by the Bonferroni-Holm method (significance level of 0.05)

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Human Genomics

ISSN: 1479-7364