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Table 3 Associations of somatic variants in oncodriver pathways with clinical data

From: Targeted panel sequencing of pharmacogenes and oncodrivers in colorectal cancer patients reveals genes with prognostic significance

Characteristics

Wild type

Mutant

pcrude/padj

 

MYC pathway

 

Stage I/II

43

0

0.004/0.056

Stage III/IV

33

7

 
 

PI3K pathway

 

Stage I/II

35

8

0.030/0.168

Stage III/IV

23

17

 
 

ICB1 gene set

 

Stage I/II

15

28

0.003/0.056

Stage III/IV

3

37

 
 

RTK-RAS pathway

 

Stage I/II

11

7

0.033/0.196

Stage III/IV

16

39

 
  1. *Numbers of patients presented
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Human Genomics

ISSN: 1479-7364