Fig. 2
From: FiTMuSiC: leveraging structural and (co)evolutionary data for protein fitness prediction
Scatter plots of paired \(\mathcal {Z}_{\text {str}}\) and \(\mathcal {Z}_{\text {evo}}\) values for all single-site mutations in HMBS. Mutations of a the catalytic residues K98, D99, R149, R150, R167, R173 and C261, b the salt bridge residues E250 and R116 and c the hydrophobic cluster residues V124, I186 and L193 are highlighted in purple