Fig. 5

Functional enrichment of the indicated HIGs. A GSEA analysis of MR1, TNFSF13B, and CCL25. B Schematic illustration of HIGs promoting intestinal inflammation. CCL25 and TNFSF13B were enriched in hsa04672 -Intestinal immune network for IgA production. Besides, Céline Mortier et al. found that MR1 promotes intestinal inflammation by activating MAIT to produce pro-inflammatory factors