Fig. 3

Quantification of cfDNA (A) and cfRNA (B) extracted from healthy donor plasma with six (co-)purification kits using different input volumes. Per assay the mean concentration of the tube and donors was taken, error bars indicate standard errors. Black horizontal lines indicate geometric means of the four assays. MIR: miRNeasy Serum/Plasma kit, MIRA: miRNeasy Serum/Plasma Advanced kit, MAX: Maxwell ccfDNA plasma kit, CCF: QIAamp ccfDNA/RNA Kit, MAPss: MagNA Pure 24 Total NA Isolation Kit (Single Strand protocol), MAPds: MagNA Pure 24 Total NA Isolation Kit (Double Strand protocol), CAT: iCatcher Circulating cfDNA/cfRNA. Numbers after kit abbreviation indicate plasma input volumes in mL