Fig. 1

Data preprocessing and differential expression gene analysis. Boxplot of the merged matrix of transcriptome data A before and B after batch effect removal and normalization. C Volcano plot of DEGs. Top 10 DEGs (sorted by adj. p value) in the up-regulated and down-regulated groups. D Heatmap of DEGs. Top 10 DEGs (sorted by |log2FC|) in the up-regulated and down-regulated groups